81377 München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Professor. Haass started to work on Alzheimer's disease (AD) in 1990 at a time, when very little was known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion rein this field that Aß may be produced from its precursor in a physiologically normal pathway and not necessarily rein a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding was a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved rein generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production hinein patients.
The practical side is taken care of hinein our top-notch driving-school vehicles, each equipped with a double-pedal Struktur. If requested, we can also provide you with tuition in an automatic car at ur driving school rein Munich.
We are the new, modern Munich driving school for Schwabing and Maxvorstadt. On three evenings a week, our fully-equipped driving school will give you the opportunity to become familiar with the theory – quickly and thoroughly.
Christian Haass, Professor of Metabolic Biochemistry at LMU Munich and spokesperson for the DZNE Munich, is known for his groundbreaking research rein Alzheimer's disease. His work focuses on the molecular and cellular mechanisms of this disease in order to gain fundamental insights into its development.
Leichte vierrädrige Straßen-Quads mit einer Nenndauerleistung/Nutzleistung von nicht eine größere anzahl denn 4 kW außerdem vierrädrige Leichtkraftfahrzeuge mit einer Nenndauerleistung/Nutzleistung von nicht eine größere anzahl als 6 kW, jeweils mit nicht etliche denn beide Sitzplätzen, einer durch die Bauart bestimmten Höchstgeschwindigkeit von nicht mehr wie 45 stundenkilometer, einer maximalen Leermasse von 425 kg und einem Fremdzündungsmotor mit einem Hubraum von nicht mehr wie 50 zentimeter³ oder einem Selbstzündungsmotor mit einem Hubraum von nicht eine größere anzahl denn 500 cm³ oder einer anderen Antriebsform.
Together with an interdiziplinary team he uncovered the molecular mechanisms of Alzheimer's disease and identified target molecules for therapeutic treatment.
Yes, a trial lesson is always possible and of course free of charge; if you decide to register with us, this trial lesson will be credited to you as "attended". I would like to register at Momo's Driving School. When can I come by?
einer elektrischen Antriebsmaschine oder einem Verbrennungsmotor mit einem Hubraum von nicht mehr als 50 zentimeter³ oder
Inhibition of secretases as a therapeutic approach requires detailed knowledge about the physiological functions and biochemical properties of these enzymes to avoid unwanted side effects. Christian Haass was the first to demonstrate a physiological function for beta-secretase. He showed that this protease is critically required for the regulation of myelination. Furthermore, he identified a novel APP processing pathway, which was overlooked for more than 20 years and which has strong implications for clinical trials using beta-secretase inhibitors. He welches also the first to identify the highly complicated subunit composition of gamma-secretase. All these findings not only helped to understand several signaling pathways critically involved rein hier klicken brain development (such as myelination and cell differentiation) but also provided the Lager for several current therapeutic approaches.
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Where can I find an economical first-aid course? We also offer courses daily in the Munich city area. They are all held rein classrooms adjacent to U/S-Bahn stations. Moosach
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Next to the Ostfriedhof bus and tram stop Can I take a trial lesson in the theoretical course rein order to get an impression of the atmosphere?
If you are lacking driving practice or simply haven't driven a car hinein a long time and have got out of the habit, we can help you get back into it with a few refresher lessons.